Pure L-Citrulline – 3 g L-Citrulline per daily dose, precursor of arginine and nitric oxide (NO)

Pure L-Citrulline contains an amino acid that the body converts into L-arginine more reliably than if you were to take pure arginine. The latter, in fact, largely does not survive the first pass through the liver, where it is broken down before it can enter circulation.¹ Citrulline, however, passes through and is converted into arginine only afterwards, thereby increasing its levels in the plasma more reliably than arginine itself.¹ This may sound like a detour, but it is precisely why it works better. Arginine is, meanwhile, the starting substance for the production of nitric oxide (NO), a molecule that contributes to vasodilation and blood flow in blood vessels.¹ In four capsules, you will find 3 g of L-Citrulline.

The second difference lies in tolerability. Arginine at higher doses more frequently leads to digestive issues, whereas citrulline was well tolerated in studies even at doses several times higher than the amount contained in one daily serving.¹ Three grams is not an arbitrary number. Studies focusing on citrulline and athletic performance most commonly work with a range of 2.4 to 6 g per day.²,⁵

Pure Citrulline or Citrulline Malate?

The most widespread form on the market is citrulline malate in a 2:1 ratio, meaning citrulline combined with malic acid. The difference between it and pure citrulline is not in the effect, but in how much of the declared gram weight consists of citrulline itself.

In a 2:1 ratio, citrulline accounts for approximately two-thirds of the weight. Six grams of citrulline malate thus corresponds to approximately 4 g. The 3 g of pure L-Citrulline contained therefore corresponds to approximately 4.5 g of citrulline malate in a 2:1 ratio.

Why take L-Citrulline

Increased blood flow to working muscles is what underlies the sensation of muscle pump sought after during training, primarily by strength athletes. L-Citrulline is currently the most closely monitored NO precursor in this area and more reliably increases plasma arginine levels than arginine itself.¹

Who it is suitable for

• You want to feel the pump during strength training: Pump is the sensation of muscle fullness and is related to blood flow to working muscles. Citrulline is the most researched NO precursor in this context, and its influence on athletic performance is the subject of a dedicated literature review.⁶
• You run or cycle: In endurance exercise, research attention focuses on oxygen management during performance³ and on the kinetics of its uptake.⁴
• You train in the evening: Unlike stimulatory pre-workouts, it does not contain caffeine. You can therefore take your dose even an hour before training without it disrupting your sleep.
• You are assembling your own pre-workout: A single-ingredient product allows you to combine it precisely according to your needs, for example with beta-alanine. With ready-made blends, you do not know exactly how much of each ingredient they contain.
• You cannot tolerate the sour taste of citrulline powder: The acidity of the powder form is pronounced and does not suit many people. In capsule form, you do not need to worry about it at all.
• You are taking GLP-1 medications (Ozempic, Wegovy, Mounjaro): The capsule contains no calories or sugar and does not take up space in your diet, which is practical when appetite is suppressed.

How to take Pure L-Citrulline

• Training days: Take 4 capsules approximately 30 to 60 minutes before training, i.e., in advance, to allow time for blood arginine levels to rise before exertion.¹
• Non-training days: Any time during the day.

Pure L-Citrulline and its benefits

• 3 g of L-Citrulline per daily dose
• The body converts it into arginine, the starting substance for the production of nitric oxide (NO)
• Single-ingredient composition for your own combinations with other substances
• Capsules without the sour taste of citrulline powder
• Does not contain caffeine

Sources and Scientific References

1. Schwedhelm E, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol. 2008;65(1):51–59.
2. Gonzalez AM, Trexler ET. Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. J Strength Cond Res. 2020;34(5):1480–1495.
3. Suzuki T, et al. Oral L-citrulline supplementation enhances cycling time trial performance in healthy well-trained males: a double-blind randomized placebo-controlled 2-way crossover study. J Int Soc Sports Nutr. 2016;13:6.
4. Bailey SJ, et al. L-Citrulline supplementation improves O₂ uptake kinetics and high-intensity exercise performance in humans. J Appl Physiol. 2015;119(4):385–395.
5. Gough LA, et al. A critical review of citrulline malate supplementation and exercise performance. Eur J Appl Physiol. 2021;121(12):3283–3295.
6. Trexler ET, et al. Acute Effects of Citrulline Supplementation on High-Intensity Strength and Power Performance: A Systematic Review and Meta-Analysis. Sports Med. 2019;49(5):707–718.

Nutrition facts

Warnings

Do not exceed the recommended daily dose. The product is not a substitute for a varied and balanced diet and a healthy lifestyle. The product is not intended for children, pregnant, or breastfeeding women. Store out of reach of small children. Store in a dry place away from sunlight at room temperature.

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