{"id":535335,"date":"2024-03-12T10:35:22","date_gmt":"2024-03-12T09:35:22","guid":{"rendered":"https:\/\/gymbeam.com\/blog\/?p=535335"},"modified":"2026-04-17T09:43:20","modified_gmt":"2026-04-17T07:43:20","slug":"ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for","status":"publish","type":"post","link":"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/","title":{"rendered":"Ozempic, Wegovy and Other Weight Loss Medications: How Do They Work and Who Are They Suitable for?"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_72 ez-toc-wrap-left counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#Why_are_weight_loss_medications_such_a_hot_topic\" title=\"Why are weight loss medications such a hot topic?\">Why are weight loss medications such a hot topic?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#How_do_weight_loss_medications_work\" title=\"How do weight loss medications work?\">How do weight loss medications work?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#What_are_the_mechanisms_of_action_of_weight_loss_medications\" title=\"What are the mechanisms of action of weight loss medications?\">What are the mechanisms of action of weight loss medications?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#What_weight_loss_medications_do_we_know\" title=\"What weight loss medications do we know?\">What weight loss medications do we know?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#Who_are_weight_loss_medications_intended_for\" title=\"Who are weight loss medications intended for?\">Who are weight loss medications intended for?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#Is_simply_taking_medications_enough_when_you_need_to_lose_weight\" title=\"Is simply taking medications enough when you need to lose weight?\">Is simply taking medications enough when you need to lose weight?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#Who_should_avoid_weight_loss_medications\" title=\"Who should avoid weight loss medications?\">Who should avoid weight loss medications?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#Can_weight_loss_medications_interact_with_other_drugs\" title=\"Can weight loss medications interact with other drugs?\">Can weight loss medications interact with other drugs?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#What_is_the_ideal_approach_to_taking_weight_loss_medications\" title=\"What is the ideal approach to taking weight loss medications?\">What is the ideal approach to taking weight loss medications?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#How_do_medications_differ_from_weight_loss_supplements\" title=\"How do medications differ from weight loss supplements?\">How do medications differ from weight loss supplements?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/#What_should_you_remember\" title=\"What should you remember?\">What should you remember?<\/a><\/li><\/ul><\/nav><\/div>\n\n<div class=\"wp-block-group has-background\" style=\"background-color:#ededed\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p><strong>Ozempic, Wegovy<\/strong>, and other anti-obesity medications are weight-loss drugs available exclusively on prescription. Orlistat <strong>(Xenical, Alli)<\/strong> limits fat absorption from food by approximately <strong>30 %<\/strong>. Naltrexone\/bupropion <strong>(Mysimba)<\/strong> suppresses appetite by affecting neurotransmitters in the brain and led to an average weight loss of <strong>6 %<\/strong> over <strong>48 weeks<\/strong>. Liraglutide <strong>(Saxenda)<\/strong>, semaglutide <strong>(Ozempic, Wegovy, Rybelsus)<\/strong>, and tirzepatide <strong>(Mounjaro)<\/strong> mimic the intestinal hormone <strong>GLP-1<\/strong>. Saxenda reduces caloric intake by approximately <strong>16 %<\/strong>, and semaglutide led to an average weight loss of <strong>17 %<\/strong> over <strong>68 weeks<\/strong>. Unlike dietary supplements, weight-loss drugs undergo mandatory clinical trials approved by regulatory authorities. <\/p>\n\n\n\n<p><br>The drugs are intended for people with obesity (<strong>BMI over 30 kg\/m\u00b2<\/strong>) or overweight (a <strong>BMI over 27 kg\/m\u00b2<\/strong>) with associated conditions, such as type 2 diabetes or cardiovascular disease. For healthy individuals, the risks outweigh the benefits. Anti-obesity drugs can interact with other medications, including warfarin and epilepsy drugs, and without a permanent lifestyle change, a yo-yo effect occurs after discontinuing them.<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>&#8220;And aren&#8217;t there any pills for that?&#8221; You&#8217;ve probably thought something similar when trying to <strong>lose weight<\/strong>. Perhaps you were even more captivated by the idea of this simple solution when you recently learned that celebrities like Elon Musk have quickly achieved their desired shape thanks to the miracles hidden behind the names <strong>Ozempic and Wegovy.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Weight loss medications<\/strong>, also known as <strong>anti-obesity drugs<\/strong>, have quickly made their mark on the world, offering many a glimmer of hope. After all, the idea of simply taking a weight loss pill with breakfast to become slim and fit effortlessly seems enticing, especially when headlines from Hollywood suggest that this might serve as a weapon against the growing obesity epidemic at our fingertips. But is it really that simple, or is there more complexity to these medications?&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[8,16]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading is-style-default\">This article will cover the following weight loss medications:<\/h3>\n\n\n\n<div class=\"wp-block-group is-nowrap is-layout-flex wp-container-core-group-is-layout-ad2f72ca wp-block-group-is-layout-flex\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-orange-background-color has-background wp-element-button\" href=\"#xenical-alli\" style=\"border-radius:0px\">Xenical, Alli<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-orange-background-color has-background wp-element-button\" href=\"#mysimba-contrave\" style=\"border-radius:0px\">Mysimba, Contrave<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-orange-background-color has-background wp-element-button\" href=\"#saxenda\" style=\"border-radius:0px\">Saxenda<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-orange-background-color has-background wp-element-button\" href=\"#ozempic-wegovy-rybelsus\" style=\"border-radius:0px\">Ozempic, Wegovy, Rybelsus<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Why_are_weight_loss_medications_such_a_hot_topic\"><\/span>Why are weight loss medications such a hot topic?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Who wouldn&#8217;t be tempted to lose weight with the wave of a magic wand? <strong>Changing one&#8217;s diet, exercise habits,<\/strong> and overall <strong>lifestyle<\/strong> is quite challenging and often ends in failure. Understandably, we eagerly embrace anything that might <strong>simplify<\/strong> weight loss for us.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Many people imagine weight loss medications as a quick route to their desired body shape. Media reports, especially when they attribute weight loss success to celebrities like Oprah Winfrey or Sharon Osbourne, often reinforce this idea. Their effectiveness is evident, and that&#8217;s why so many people think that there&#8217;s finally something to break them out of the <strong>endless cycle of dieting and yo-yo effects. <\/strong><sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[20,25,26]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>These medications become even more appealing when you know that doctors prescribe them for <strong>obesity therapy<\/strong>. Naturally, you might assume that if they help with obesity, they could also be useful for you.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"749\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1924223939_5000-1124x749.jpg\" alt=\"What are weight loss medications good for?\" class=\"wp-image-532936\" title=\"What are weight loss medications good for?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1924223939_5000-1124x749.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1924223939_5000-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1924223939_5000-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1924223939_5000-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_do_weight_loss_medications_work\"><\/span>How do weight loss medications work?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Weight loss medications are not just a gimmick. After all, <strong>obesity specialists<\/strong> routinely prescribe them to patients with <strong>obesity<\/strong> who need a helping hand with weight loss. These medications are primarily intended for them.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>In weight loss pills, there are active ingredients that can affect various physiological processes in our bodies and truly <strong>help with weight loss. <\/strong>The fact that they are <strong>medications<\/strong> also helps their credibility. For a pill to become a medication, it must undergo numerous <strong>tests<\/strong> and <strong>clinical trials<\/strong>. When these trials show that it <strong>works<\/strong> and is <strong>safe<\/strong> to use (in prescribed doses), it can be <strong>registered as a medication.<\/strong> In the European Union, the <strong>European Medicines Agency<\/strong> (EMA) oversees this pivotal step, while in the United States, it is the responsibility of the <strong>Food and Drug Administration<\/strong> (FDA).&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[15]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Not all weight loss medications are the same. Under names like the well-known Ozempic or Saxenda, there are <strong>several mechanisms of action.<\/strong> These medications, therefore, work in different ways and can shuffle the cards in several physiological processes in our bodies.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"749\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1226980064_5000-1124x749.jpg\" alt=\"How do weight loss medications work?\" class=\"wp-image-532953\" title=\"How do weight loss medications work?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1226980064_5000-1124x749.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1226980064_5000-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1226980064_5000-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1226980064_5000-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_are_the_mechanisms_of_action_of_weight_loss_medications\"><\/span>What are the mechanisms of action of weight loss medications?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">1. Suppressing appetite<\/h3>\n\n\n\n<p>These medications act on centers in the brain and influence how you perceive <strong>hunger<\/strong> or <strong>satiety<\/strong>. They can make you feel <strong>less hungry<\/strong>, and they often <strong>reduce cravings<\/strong> for sweet and salty snacks, which are commonly the culprit of the issue. They also help you <strong>feel full faster<\/strong>, even <strong>after eating a smaller portion<\/strong>. This allows you to reduce food intake more easily and thus achieve a caloric deficit for weight loss. You might recognize these medications by names like <strong>Mysimba<\/strong> or <strong>Adipex retard.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">2. Limiting nutrient absorption<\/h3>\n\n\n\n<p>Some medications aim to prevent the <strong>complete digestion of nutrients<\/strong> (usually fats or carbohydrates). These nutrients then cannot be absorbed into the bloodstream and converted into energy, <strong>reducing calorie intake.<\/strong> For example, a meal that has 400 kcal might yield only 300 kcal when combined with one of these medications, as the remaining calories are expelled from the body in the form of <strong>undigested fat<\/strong> or <strong>carbohydrates<\/strong>. In a way, they can act as carbohydrate or fat blockers. A well-known example of this is <strong>Orlistat<\/strong>.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">3. Mimicking hormones of the digestive system<\/h3>\n\n\n\n<p>Our digestive system naturally produces so-called <strong>incretins<\/strong>, hormones such as GLP-1, which further influence the secretion of insulin and <strong>glucagon<\/strong>. On one hand, they promote the production of insulin, which can then lower blood sugar levels (glycemia). This is why these medications are primarily intended for the treatment of <strong>type 2 diabetes.&nbsp;<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>However, they have also proven effective in weight loss, particularly due to their ability to <strong>slow down gastric emptying<\/strong>. This keeps the stomach fuller for longer, <strong>prolonging the time until hunger strikes<\/strong>. Additionally, they help promote satiety by influencing <strong>the brain centers<\/strong> responsible for <strong>feelings of hunger<\/strong> and <strong>fullness<\/strong>.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n    <link href=\"https:\/\/gymbeam.com\/blog\/wp-content\/themes\/wp-gymbeam-blog-theme\/css\/vue\/index.css\" rel=\"preload\" as=\"style\">\n    <link href=\"https:\/\/gymbeam.com\/blog\/wp-content\/themes\/wp-gymbeam-blog-theme\/js\/vue\/chunk-vendors.js\" rel=\"preload\" as=\"script\">\n    <link href=\"https:\/\/gymbeam.com\/blog\/wp-content\/themes\/wp-gymbeam-blog-theme\/js\/vue\/index.js\" rel=\"preload\" as=\"script\">\n    <link data-no-optimize=\"1\" href=\"https:\/\/gymbeam.com\/blog\/wp-content\/themes\/wp-gymbeam-blog-theme\/css\/vue\/index.css\" rel=\"stylesheet\">\n\n    <h2>\n        You might be interested in these products:    <\/h2>\n\n    <div data-app=\"recommended\" data-products=\"47731,62779,75292,39076,81421,54646,5380,5383,28352,35419,6503,5075\" ><\/div>\n\n    <script data-no-optimize=\"1\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/themes\/wp-gymbeam-blog-theme\/js\/vue\/chunk-vendors.js\"><\/script>\n    <script data-no-optimize=\"1\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/themes\/wp-gymbeam-blog-theme\/js\/vue\/index.js\"><\/script>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_weight_loss_medications_do_we_know\"><\/span>What weight loss medications do we know?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>For someone looking to shed excess fat and turning to weight loss medications for help, there are several options available. Since a <strong>medical prescription<\/strong> is required to obtain them, it&#8217;s up to the doctor to choose the one that best targets the main problem. It&#8217;s also important to discuss with the doctor any <strong>side effects<\/strong> that may occur during use. While the following medications are generally safe, as is typical of medications, they may still come with unpleasant effects.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"xenical-alli\">1. Orlistat &#8211; Xenical, Alli<\/h3>\n\n\n\n<p>The active ingredient orlistat has been a mainstay in the weight loss medication market. It officially entered use in the European Union as early as 1998 with the registration of the first medication, <strong>Xenical<\/strong>. Xenical is still in use today and requires a <strong>medical prescription<\/strong>. Orlistat is also found in the medication <strong>Alli<\/strong>, which joined its older sibling in 2007. The younger sibling with a lower dose of orlistat can be purchased and used even <strong>without a doctor&#8217;s prescription.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">How does orlistat work?<\/h4>\n\n\n\n<p>Orlistat aims to <strong>prevent the complete digestion of fat from food.<\/strong> Undigested fat cannot be <strong>absorbed from the digestive system into the bloodstream<\/strong> and therefore cannot be <strong>converted into energy.<\/strong> By this mechanism, orlistat <strong>reduces calorie intake from food.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>It specifically targets <strong>gastric<\/strong> and <strong>pancreatic lipase<\/strong>, enzymes that break down fats into glycerol and fatty acids in the stomach and small intestine. Orlistat <strong>inhibits their activity<\/strong>, preventing some fats from being broken down, and instead, they are <strong>excreted from the body in the stool.<\/strong>&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[7,9]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Is orlistat effective?<\/h4>\n\n\n\n<p>Orlistat boasts quite respectable results. It is reported that when taken at the recommended dose before meals, it can <strong>reduce the absorption of fat from that meal by roughly 30%.<\/strong> Imagine a lunch that contains <strong>40 g of fat.<\/strong> By taking orlistat before diving into it, you can <strong>prevent the absorption of about 12 g of fat<\/strong> (30% of 40 g). Since 1 g of fat contains 9 kcal, this medication can <strong>reduce the calorie content of lunch by a total of 108 kcal.<\/strong> Of course, this only applies when the meal contains fat. That&#8217;s why it&#8217;s intended for people whose problem lies in <strong>a high-fat diet.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Does orlistat have side effects?<\/h4>\n\n\n\n<p>Although the effect of orlistat may seem like a fairy tale at first glance, it is not without side effects. The most common ones are <strong>digestive problems<\/strong> because undigested fat can cause <strong>diarrhea, gas<\/strong>, or even <strong>stool leakage.<\/strong> <strong>Abdominal pain<\/strong> or <strong>flatulence<\/strong> may also occur. When taking it, it&#8217;s also important to consider that it may reduce the absorption of fat-soluble vitamins (<a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/vitamin-a\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">A<\/a>,&nbsp;<a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/vitamin-d\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">D<\/a>,&nbsp;<a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/vitamin-e\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">E<\/a>,&nbsp;<a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/vitamin-k2-gymbeam.html\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">K<\/a>).&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[4,9]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"mysimba-contrave\">2. Naltrexone-bupropion \u2013 Mysimba, Contrave<\/h3>\n\n\n\n<p>If you&#8217;re looking for a modern medication to help reduce appetite, a combination of naltrexone and bupropion may be the right choice. In European Union countries, the medication <strong>Mysimba<\/strong> is registered, while in the USA, your doctor would prescribe <strong>Contrave<\/strong>. Both medications require a prescription.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[5]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">How does naltrexone-bupropion work?<\/h4>\n\n\n\n<p>Mysimba and Contrave target the central nervous system directly \u2013 the brain. They influence <strong>neurotransmitters<\/strong>, which are substances that transmit information between nerve cells. By affecting these messengers, they can <strong>decrease appetite and increase feelings of fullness. Better control of appetite<\/strong> ensures lower calorie intake.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>What if someone struggles with <strong>emotional eating?<\/strong> Interestingly, even in this case, these medications can lend a helping hand. They block the reward system in the brain, where <a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/blog\/dopamine-brings-joy-and-motivation-but-its-excess-can-be-harmful-do-you-need-a-dopamine-detox\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">dopamine<\/a>&nbsp;plays a key role. Dopamine is responsible for the pleasure from eating and feelings of bliss that follow indulging in a favorite treat. However, when this system is dampened, the body isn&#8217;t as <strong>drawn<\/strong> to tasty food. Mysimba and Contrave can not only <strong>reduce hunger<\/strong> and <strong>promote satiety<\/strong> but also help <strong>control cravings<\/strong> and the <strong>uncontrollable urge to snack<\/strong>.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[19]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Is naltrexone-bupropion effective?<\/h4>\n\n\n\n<p>The active ingredients naltrexone and bupropion have shown effects on body weight even when taken separately. However, clinical studies have confirmed they are <strong>more effective when used together.<\/strong> Results from a study involving 419 participants indicate that after 48 weeks, there was an average weight loss of 6%.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[2]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Does naltrexone-bupropion have side effects?<\/h4>\n\n\n\n<p>Even in this case, adverse effects relate to digestion. <strong>Nausea, vomiting,<\/strong> or <strong>constipation<\/strong> may occur. <strong>Dizziness<\/strong> or <strong>dry mouth<\/strong> are also known side effects. <strong>Increased blood pressure<\/strong>, <strong>higher heart rate<\/strong>, or <strong>insomnia<\/strong> are not uncommon among those taking these medications.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[19]<\/mark><\/sup><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"749\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1473676018_5000-1124x749.jpg\" alt=\"How does Mysimba work?\" class=\"wp-image-532971\" title=\"How does Mysimba work?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1473676018_5000-1124x749.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1473676018_5000-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1473676018_5000-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1473676018_5000-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"saxenda\">3. Liraglutide &#8211; Saxenda<\/h3>\n\n\n\n<p>Liraglutide belongs to the <strong>newer<\/strong> and <strong>more modern substances<\/strong> in the world of anti-obesity medications. It has only been on the market since 2015, known in the European Union and the United States under the commercial name Saxenda. However, its method of administration might deter some. Unlike previous medications, it is not taken in tablet form but administered <strong>once daily by injection<\/strong> under the skin.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[10,24]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">How does liraglutide work?<\/h4>\n\n\n\n<p>Liraglutide mimics the action of glucagon-like peptide-1 (GLP-1), a hormone naturally secreted in the digestive system. Similar to GLP-1, liraglutide influences parts of the brain that <strong>control appetite<\/strong>, <strong>reducing hunger<\/strong> and <strong>increasing feelings of fullness.<\/strong> It also<strong> slows down gastric emptying<\/strong>, leading to <strong>lower caloric intake and weight loss.<\/strong>&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[24]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Saxenda primarily acts as an <strong>antidiabetic medication <\/strong>for people suffering from type 2 diabetes, helping to increase insulin secretion, which aims to lower blood sugar levels.<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[24]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Is liraglutide effective?<\/h4>\n\n\n\n<p>Saxenda is now among the most popular anti-obesity medications, and for good reason. Clinical studies focusing on this medication show that it helps <strong>reduce caloric intake<\/strong> by approximately <strong>16%<\/strong>. With a daily intake of 2000 kcal, this translates to about 320 kcal saved. Considering the fact that the recommended caloric deficit is around 500 kcal, the remaining 180 kcal can quite easily be burned through walking or strength training.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[11]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>In five studies involving around 6000 individuals, it was found that on average, participants lost <strong>8% of their body weight<\/strong> (after about 40 weeks of use). Scientists also concluded that liraglutide use in people with obesity <strong>reduces the risk of developing type 2 diabetes by up to 80%.<\/strong>&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[11,24]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Does liraglutide have side effects?<\/h4>\n\n\n\n<p>Like practically any medication, liraglutide is not exempt from side effects. Digestive problems such as <strong>constipation, diarrhea, vomiting,<\/strong> or <strong>nausea<\/strong> are common.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[24]<\/mark><\/sup><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"749\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1190115881_5000-1124x749.jpg\" alt=\"How does Saxenda work?\" class=\"wp-image-532988\" title=\"How does Saxenda work?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1190115881_5000-1124x749.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1190115881_5000-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1190115881_5000-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1190115881_5000-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"ozempic-wegovy-rybelsus\">4. Semaglutide \u2013 Ozempic, Wegovy, Rybelsus<\/h3>\n\n\n\n<p>Semaglutide is perhaps the most widely known medication for weight loss today. It is hidden behind the well-known brands <strong>Ozempic<\/strong> and <strong>Wegovy<\/strong>, which boast about their effects throughout Hollywood. Alternatively, you might encounter it in the form of the medication <strong>Rybelsus.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>However, it is primarily a substance belonging to<strong> antidiabetic medications<\/strong>. Rybelsus and Ozempic should be correctly prescribed only to <strong>diabetics.<\/strong> The effect on weight loss became apparent over time, leading to the development of Wegovy, which can be prescribed for obesity treatment.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Semaglutide has gained popularity due to its <strong>rapid effects<\/strong> and perhaps its method of administration. To experience its effects, you only need to inject it once a week into your abdomen or thigh. In this case, it seems like waving a magic wand and achieving the desired figure is within reach. But not so fast. Even with Ozempic, not everything is as perfect as it seems.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">How does semaglutide work?<\/h4>\n\n\n\n<p>Semaglutide acts similarly to the previous liraglutide. It also mimics the hormone GLP-1, <strong>reducing hunger<\/strong> and <strong>promoting satiety<\/strong>, and its impact on <strong>slowing gastric emptying<\/strong> is crucial. Its advantage lies in the <strong>gradual release<\/strong> in the body, with one dose being processed over a longer period. This is why it only needs to be taken once a week.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[6,23]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>However, semaglutide is primarily intended for the treatment of <strong>type 2 diabetes,<\/strong> effectively helping to <strong>lower<\/strong> and <strong>stabilize blood sugar levels.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Is semaglutide effective?<\/h4>\n\n\n\n<p>Semaglutide isn&#8217;t just praised in the media; good results also stem from clinical studies. Research involving people with obesity who took semaglutide for 68 weeks showed an average <strong>weight loss of 17%.<\/strong> Alongside this, health parameters such as blood lipid levels or glycemia also improved.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[12]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>So what takes precedence? Diabetes or weight loss? When news spread that it helps shed pounds quickly, especially in North America, there was a rush for semaglutide. This led to a problem because diabetics started to miss out. In practice, when you start using a diabetes medication for weight loss without control, there can easily be a <strong>shortage on the market.<\/strong> <strong>Ozempic or Wegovy<\/strong> have demonstrable effects on weight loss, but primarily, their undeniable benefits should be reaped by those who <strong>truly need them for their health problems.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Does semaglutide have side effects?<\/h4>\n\n\n\n<p>When taking semaglutide, digestive problems such as <strong>constipation, vomiting,<\/strong> and <strong>nausea<\/strong> are the main concerns. If you&#8217;ve followed the media frenzy, you might have noticed that many celebrities also spoke about <strong>fatigue, dizziness,<\/strong> or increased <strong>sensitivity<\/strong> and <strong>moodiness.<\/strong>&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[23]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">What other weight loss medications do we know?<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Phentermine-topiramate<\/strong> may be familiar to you under the brand name <strong>Adipex Retard.<\/strong> It acts on the brain&#8217;s centers, effectively suppressing appetite. It was used for a long time in obesity therapy, but the European Medicines Agency recently banned it due to the risk of dependence and frequent side effects.<\/li>\n\n\n\n<li><strong>Tirzepatide<\/strong> is the active ingredient in the medication <strong>Mounjaro.<\/strong> Like semaglutide and liraglutide, it mimics the function of the GLP-1 hormone.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[18]<\/mark><\/sup><\/li>\n\n\n\n<li><strong>Setmelanotide,<\/strong> known as the medication <strong>Imcivree,<\/strong> is used to treat genetically caused obesity<span style=\"font-size: 1rem;\">.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[17]<\/mark><\/sup>&nbsp;<\/span><\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"749\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1471205967_5000-1124x749.jpg\" alt=\"How do Ozempic and Wegovy work?\" class=\"wp-image-533006\" title=\"How do Ozempic and Wegovy work?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1471205967_5000-1124x749.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1471205967_5000-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1471205967_5000-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1471205967_5000-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_are_weight_loss_medications_intended_for\"><\/span>Who are weight loss medications intended for?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>You might have thought that these pills and other weight loss medications could be the solution to the global problem of increasing overweight and obesity. If they were available to everyone, more people would <strong>successfully lose weight,<\/strong> there would be fewer cases of <strong>diabetes,<\/strong> and other <strong>metabolic diseases.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>We might even be able to <strong>lighten the load on healthcare systems<\/strong> and <strong>state budgets<\/strong>, which deifnitely doesn&#8217;t sound like a bad thing. After all, data from 2023 shows how easily, for example, average annual expenses for treating diabetes, ischemic heart disease, and myocardial infarction could be reduced in Germany. Simply lowering the BMI from 30 kg\/m<sup>2<\/sup>&nbsp;by just one unit could save an average of about 4300 euros annually. Weight loss medications could easily help with that, right? It sounds like a fairy tale, but in reality, it&#8217;s not that simple.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[3]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Are they also suitable for healthy people?<\/h3>\n\n\n\n<p>If there were a possibility to prescribe weight loss pills to absolutely everyone, we would be getting closer to that fairy tale. In reality, healthy people with just a few extra pounds of fat can actually <strong>harm<\/strong> themselves with weight loss medications. The risks simply outweigh the benefits. Just think of the side effects of Ozempic and other substances we&#8217;ve discussed.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>While these medications can help with weight loss, to be healthy, especially in the <strong>long term,<\/strong> you primarily need to adhere to a <strong>healthy lifestyle<\/strong> in all its aspects. Weight loss medications can never replace a <a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/blog\/what-is-a-healthy-diet-and-how-to-learn-to-eat-healthy\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">healthy diet<\/a>, <a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/blog\/how-to-fall-asleep-quickly-try-these-simple-tips-for-a-better-sleep\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">sleep<\/a>, or regular exercise.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Ultimately, we must also realize that these are <strong>medications.<\/strong> Just like heart or asthma medications, they are intended for people with <strong>health problems.<\/strong> Even the term <strong>&#8220;anti-obesity&#8221;<\/strong> indicates that they should be taken by people <strong>diagnosed with obesity,<\/strong> a condition that often comes with various complications. They are <strong>the final piece of the puzzle<\/strong> that comes into play when <strong>lifestyle changes alone fail to result in weight loss.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The main goal of anti-obesity medications is not aesthetics and perfecting one&#8217;s body, but rather <strong>getting rid of health complications<\/strong> associated with excess body weight. Obesity typically leads to <strong>high blood pressure, cholesterol,<\/strong> and other complications, which are direct tickets to a world full of <strong>strokes<\/strong> and <strong>heart attacks.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Officially, weight loss medications should be prescribed only in the following cases:<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>For people with obesity (BMI higher than 30 kg\/m<sup>2<\/sup>).<\/li>\n\n\n\n<li>For overweight people with a BMI over 27 kg\/m<sup>2<\/sup> who already suffer from conditions caused by excess weight (high blood pressure, atherosclerosis, or other cardiovascular problems, diabetes, etc.).&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[14]<\/mark><\/sup><\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"750\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1372616822_5000-1124x750.jpg\" alt=\"Who are weight loss medications suitable for?\" class=\"wp-image-533023\" title=\"Who are weight loss medications suitable for?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1372616822_5000-1124x750.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1372616822_5000-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1372616822_5000-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-1372616822_5000-2048x1366.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Is_simply_taking_medications_enough_when_you_need_to_lose_weight\"><\/span>Is simply taking medications enough when you need to lose weight?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Let&#8217;s imagine you want to lose weight and meet the conditions for medication prescription. Will you be saved by taking one pill every morning from now on? It would be great if you could shed unwanted pounds by simply taking pills while washing them down with Coca-Cola and eating pizza. Unfortunately, we don&#8217;t live in a dream world, and it simply doesn&#8217;t work like that.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>In this case, too, it holds true that to lose weight, you need to <strong>adjust your lifestyle first.<\/strong> Weight loss pills are not omnipotent and ideally should only complement a <a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/blog\/tailored-meal-plan-complete-guide-on-planning-your-diet-based-on-calories-and-macros\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\"><strong>weight loss diet<\/strong><\/a><strong>, regular physical activity,<\/strong> and other aspects of a <strong>healthy lifestyle. <\/strong>Saxenda, Ozempic, and other medications should always come into play as a last resort, only to <strong>enhance<\/strong> and <strong>accelerate weight loss.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Not only will you <strong>lose weight more easily<\/strong> and significantly improve your health, but you will also significantly increase the chance of <strong>maintaining weight loss even after discontinuing the medications.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Because if you rely solely on medications, you&#8217;ll likely lose weight, but what happens after you stop taking them? When you no longer have this crutch, the pounds of fat will sooner or later come back, probably with interest. Weight loss medications are not exempt from the old familiar <strong>yo-yo effect.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_should_avoid_weight_loss_medications\"><\/span>Who should avoid weight loss medications?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Every medication has its specifics, but generally speaking, these medications should not be prescribed in the following cases:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>For pregnant<\/strong> and <strong>breastfeeding women.<\/strong><\/li>\n\n\n\n<li>In most cases, for <strong>children,<\/strong> although a doctor may decide on exceptions.<\/li>\n\n\n\n<li>For people with <a class=\"ek-link\" href=\"https:\/\/gymbeam.com\/blog\/eating-disorders-why-they-occur-what-are-their-symptoms-and-consequences\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"(opens in a new tab)\"><strong>eating disorders (EDs)<\/strong><\/a>&nbsp;or other psychiatric diagnoses.<\/li>\n\n\n\n<li>In the presence of various <strong>illnesses.<\/strong> However, these cases are very individual for each medication, and it&#8217;s up to the doctor whether to prescribe the medication or not.<\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1124\" height=\"749\" src=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-883957862-1124x749.jpg\" alt=\"Who are weight loss medications not suitable for?\" class=\"wp-image-533039\" title=\"Who are weight loss medications not suitable for?\" srcset=\"https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-883957862-1124x749.jpg 1124w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-883957862-400x267.jpg 400w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-883957862-1536x1024.jpg 1536w, https:\/\/gymbeam.com\/blog\/wp-content\/uploads\/2024\/03\/iStock-883957862-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1124px) 100vw, 1124px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Can_weight_loss_medications_interact_with_other_drugs\"><\/span>Can weight loss medications interact with other drugs?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Every medication becomes part of numerous physiological processes in the body. Therefore, it&#8217;s very likely that some of them will <strong>cross paths<\/strong> and interfere with each other. The likelihood increases with the number of medications a person takes. Weight loss medications are no exception, and there are many possible interactions. It&#8217;s primarily <strong>up to doctors<\/strong> to ensure that the individual medications a person takes do not interfere with each other.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>An example of such an interaction is <strong>orlistat,<\/strong> which can <strong>reduce the absorption of epilepsy medications.<\/strong> Furthermore, when combined with warfarin (a blood thinner), it can increase bleeding.&nbsp;<sup><mark class=\"has-inline-color has-orange-color\" style=\"background-color: rgba(0, 0, 0, 0);\">[22]<\/mark><\/sup><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_is_the_ideal_approach_to_taking_weight_loss_medications\"><\/span>What is the ideal approach to taking weight loss medications?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>No medication is a miracle that will save us on its own and cure obesity. In any case, it&#8217;s important to start with <strong>lifestyle changes.<\/strong> Set up a <strong>reduction diet,<\/strong> choose appropriate <strong>regular physical activity,<\/strong> address <strong>sleep problems,<\/strong> and <strong>control stress.<\/strong> Only then should medications be considered. How long to take them depends mainly on how successful the weight loss is and at what weight the weight loss starts.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"How_do_medications_differ_from_weight_loss_supplements\"><\/span>How do medications differ from weight loss supplements?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>You surely know that there are not only medications but also weight loss supplements promising getting rid of excess water, weight control, and other great benefits. As examples we can mention Forfemina, Lipoxal, Diterpex, or Bellasin.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>How do these supplements differ from medications besides the fact that you can buy them right now without any prescription from a doctor? The main and most important difference is their <strong>effectiveness.<\/strong> Weight loss supplements <strong>have not undergone clinical trials.<\/strong> Unlike medications, they have come to the market without professional organizations confirming their efficacy.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_should_you_remember\"><\/span>What should you remember?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>When the media filled with information about Hollywood stars losing weight at lightning speed thanks to Ozempic and Wegovy (semaglutide), the world was excited about the idea of <strong>easy weight loss<\/strong> and the <strong>end of endless dieting.<\/strong> And actually, somewhat rightfully so, because weight loss medications are no charlatanism and really work. Nevertheless, every enchanting tale harbors a twist, and this scenario is no exception.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Weight loss medications are simply medications, so <strong>they are not intended for healthy people.<\/strong> They should be given to those with <strong>health problems,<\/strong> namely people with obesity and associated complications. For healthy people with a few extra pounds, they are <strong>more risky than beneficial.<\/strong> Even amidst the advancements of modern medicine, the cornerstone of weight loss remains a <strong>caloric deficit<\/strong> rooted in a <strong>balanced lifestyle.<\/strong><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Did the article teach you something new? If you liked it, we would appreciate if you shared it with your friends and acquaintances.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><a href=\"https:\/\/gymbeam.com\/healthy-food\" target=\"_blank\" class=\"category-button\">\n\t<span class=\"label\">\n\t\tHealthy food\t<\/span>\n\t<svg class=\"icon-cart\" focusable=\"false\">\n\t\t<use xlink:href=\"#icon-cart\"><\/use>\n\t<\/svg>\n<\/a><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><a href=\"https:\/\/gymbeam.com\/protein-for-weight-loss\" target=\"_blank\" class=\"category-button\">\n\t<span class=\"label\">\n\t\tProtein for Weight Loss\t<\/span>\n\t<svg class=\"icon-cart\" focusable=\"false\">\n\t\t<use xlink:href=\"#icon-cart\"><\/use>\n\t<\/svg>\n<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Have you heard about Ozempic and Wegovy? These are weight loss medications that are currently making waves in Hollywood. They represent a breakthrough in weight loss that could potentially eliminate the need for diets, but is it really the best path forward? Today&#8217;s article will reveal the truth.<\/p>\n","protected":false},"author":156,"featured_media":532915,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[93],"tags":[7433,7619,7349,6365],"filter_section":[],"filter_attribute":[],"class_list":{"0":"post-535335","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-how-to-lose-weight","8":"tag-body-fat","9":"tag-health","10":"tag-nutrition","11":"tag-weight-loss","12":"h-entry","13":"hentry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ozempic, Wegovy and Other Weight Loss Medications: How Do They Work and Who Are They Suitable for? - GymBeam Blog<\/title>\n<meta name=\"description\" content=\"Ozempic, Wegovy, and Saxenda are modern weight loss medications. How do they work, how do they help with weight loss, and what are side effects?\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gymbeam.com\/blog\/ozempic-wegovy-and-other-weight-loss-medications-how-do-they-work-and-who-are-they-suitable-for\/\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ozempic, Wegovy and Other Weight Loss Medications: How Do They Work and Who Are They Suitable for? - GymBeam Blog\" \/>\n<meta property=\"og:description\" content=\"Ozempic, Wegovy, and Saxenda are modern weight loss medications. 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